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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PKN1
All Species:
10.61
Human Site:
T527
Identified Species:
17.95
UniProt:
Q16512
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16512
NP_002732.3
942
103932
T527
R
R
L
I
P
N
A
T
G
T
G
T
F
S
P
Chimpanzee
Pan troglodytes
XP_512443
1169
127241
T754
R
R
L
I
P
N
A
T
G
T
G
T
F
S
P
Rhesus Macaque
Macaca mulatta
XP_001110500
1011
111864
S579
M
N
L
L
P
P
C
S
S
P
S
T
I
S
P
Dog
Lupus familis
XP_542019
1076
118222
T660
R
R
L
I
P
N
A
T
A
T
S
T
F
S
P
Cat
Felis silvestris
Mouse
Mus musculus
P70268
946
104392
V530
R
R
L
I
P
S
A
V
A
T
G
T
F
S
P
Rat
Rattus norvegicus
Q63433
946
104449
V530
R
R
L
I
P
N
A
V
A
T
G
S
F
S
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506565
993
109767
G567
L
G
L
L
P
P
C
G
S
P
S
S
T
L
S
Chicken
Gallus gallus
XP_422357
1013
114806
I551
G
R
L
V
R
R
A
I
P
T
V
N
H
S
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_689331
948
107057
I536
V
R
L
L
R
N
A
I
P
T
V
N
N
T
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13678
634
71138
C253
P
G
Q
S
F
R
S
C
A
L
S
V
D
S
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34885
707
80133
K326
M
S
I
R
S
K
K
K
P
S
I
M
T
D
T
Sea Urchin
Strong. purpuratus
XP_787090
799
90414
G387
A
D
S
S
E
S
A
G
S
N
S
Q
E
G
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P24583
1151
131500
D712
M
E
L
E
I
K
Q
D
S
G
E
I
Q
E
D
Red Bread Mold
Neurospora crassa
P87253
1142
127954
Q685
M
A
P
K
H
S
S
Q
P
S
Q
A
G
S
I
Conservation
Percent
Protein Identity:
100
79.3
38.7
83
N.A.
91.6
91.9
N.A.
42.2
57.6
N.A.
66.7
N.A.
29
N.A.
27.8
48.5
Protein Similarity:
100
79.9
52.6
84.3
N.A.
94.7
94.6
N.A.
56.1
72.1
N.A.
79.5
N.A.
42.8
N.A.
43.4
61.7
P-Site Identity:
100
100
33.3
86.6
N.A.
80
80
N.A.
13.3
33.3
N.A.
33.3
N.A.
6.6
N.A.
0
6.6
P-Site Similarity:
100
100
46.6
86.6
N.A.
86.6
86.6
N.A.
26.6
40
N.A.
46.6
N.A.
13.3
N.A.
13.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.8
28.3
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.4
45.1
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
0
0
0
58
0
29
0
0
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
15
8
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
0
0
0
0
8
0
0
0
0
8
8
8
% D
% Glu:
0
8
0
8
8
0
0
0
0
0
8
0
8
8
0
% E
% Phe:
0
0
0
0
8
0
0
0
0
0
0
0
36
0
0
% F
% Gly:
8
15
0
0
0
0
0
15
15
8
29
0
8
8
22
% G
% His:
0
0
0
0
8
0
0
0
0
0
0
0
8
0
0
% H
% Ile:
0
0
8
36
8
0
0
15
0
0
8
8
8
0
8
% I
% Lys:
0
0
0
8
0
15
8
8
0
0
0
0
0
0
0
% K
% Leu:
8
0
72
22
0
0
0
0
0
8
0
0
0
8
8
% L
% Met:
29
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
0
8
0
0
0
36
0
0
0
8
0
15
8
0
0
% N
% Pro:
8
0
8
0
50
15
0
0
29
15
0
0
0
0
43
% P
% Gln:
0
0
8
0
0
0
8
8
0
0
8
8
8
0
0
% Q
% Arg:
36
50
0
8
15
15
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
8
8
15
8
22
15
8
29
15
36
15
0
65
8
% S
% Thr:
0
0
0
0
0
0
0
22
0
50
0
36
15
8
8
% T
% Val:
8
0
0
8
0
0
0
15
0
0
15
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _